What: These are “constructive comments” about clinical Alzheimer’s dementia (AD) research, from a cancer doctor’s clinical research perspective.
It seems to him that research philosophy, strategy and infrastructure, as much as funding available or number of investigators, significantly differ in clinical AD research vs. cancer clinical research. There still may be some strategies or actions [based on oncology’s history] that might accelerate the discovery of disease-modifying therapy, or perhaps change the “trajectory” of this work, while recognizing that brilliant, hard work is being done everyday in AD research.
If anyone really reads these postings, they will see recurrent ideas, but please understand that they were written and adapted for different audiences. On the other hand, the blog does assume that the reader knows something of the medical research structure in the US, and may use jargon.
Many of the pieces were previously published. Some are Op-Eds, but some are comments in response to research articles, postings or announcements about AD research. Links are provided for the original site, if available, or other related publications.
“Matter of Fact“, originally published in the journal Neurology, is a poem by the author that reflects a moment in the AD diagnostic process.
(image: NIH public domain, MRI sagittal brain with color)